Endocrine Abstracts

Background: The prevalence of small intestine neuroendocrine tumors (SI-NETs) is increasing. Disease progression is often slow, treatment options and long-term survival rates have improved. Health-related quality of life (HRQoL) is considered an important measure of patients’ perception of the burden of their disease and the impact of treatment modalities. Despite this, data on whether improvements in treatment options and survival rates also translate into improved HRQoL...

Introduction: In small intestinal neuroendocrine tumors (SI-NET), unphysiological exposure to serotonin is considered as a major pathogenic factor predisposing to the development carcinoid heart disease (CHD), a complication of carcinoid syndrome associated with poor prognosis. The ability of biomarkers to predict the development of CHD is limited. The aim of our prospective study was to assess risk factors of CHD development and mortality in SI-NET.Meth...